Adding Evidence Type Representation to DIDEO

نویسندگان

  • Mathias Brochhausen
  • Philip E. Empey
  • Jodi Schneider
  • William R. Hogan
  • Richard D. Boyce
چکیده

In this poster we present novel development and extension of the Drug-drug Interaction and Drug-drug Interaction Evidence Ontology (DIDEO). We demonstrate how reasoning over this extension of DIDEO can a) automatically create a multi-level hierarchy of evidence types from descriptions of the underlying scientific observations and b) automatically subsume individual evidence items under the correct evidence type. Thus DIDEO will enable evidence items added manually by curators to be automatically categorized into a drug-drug interaction framework with precision and minimal effort from curators. As with all previous DIDEO development this extension is consistent with OBO Foundry principles. Keywords—drug-drug interaction; potential drug-drug interaction; evidence types; biomedical ontologies

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Formalizing Evidence Type Definitions for Drug-Drug Interaction Studies to Improve Evidence Base Curation

In this research we aim to demonstrate that an ontology-based system can categorize potential drug-drug interaction (PDDI) evidence items into complex types based on a small set of simple questions. Such a method could increase the transparency and reliability of PDDI evidence evaluation, while also reducing the variations in content and seriousness ratings present in PDDI knowledge bases. We e...

متن کامل

Efficacy of adding glutazone to the maximum dose of glibenclamide and metformin resistant on type 2 diabetic patients

Background: To evaluate the efficacy of adding the glutazone to maximum dose of sulfonylurea and metformin in patients with poorly controlled type 2 diabetes. Methods: Ninety six patients with type 2 diabetes who had failed medical therapy with maximal-dosage of metformin and glibenclamide received glutazone. Fasting blood sugar (FBS), 2 hours postprandial (2hpp) glucose, hemoglobin A1C, chol...

متن کامل

The effect of social cognitive representation on the mental property of the body: Evidence based on rubber hand illusion

Mental representations are to be considered as the most advanced aspects of human cognition and in addition to their own physical representations, representations of social cognition of others can also affect the mental experience of each person's ownership of their body. Accordingly, the present research as a quasi-experimental study based on repeated measures, was conducted in order to invest...

متن کامل

ON THE USE OF KULSHAMMER TYPE INVARIANTS IN REPRESENTATION THEORY

Since 2005 a new powerful invariant of an algebra has emerged using the earlier work of Horvath, Hethelyi, Kulshammer and Murray. The authors studied Morita invariance of a sequence of ideals of the center of a nite dimensional algebra over a eld of nite characteristic. It was shown that the sequence of ideals is actually a derived invariant, and most recently a slightly modied version o...

متن کامل

Organization of Gatekeeping and Mental Framework in the System of Representation and Hierarchical Relational Structures of the Modern Society

Critical discourse analysis as a type of social practice reveals how linguistic choices enable speakers to manipulate the realizations of agency and power in the representation of action.The present study examines the relationship between language and ideology and explores how such a relationship is represented in the analysis of spoken text and to show how declarative knowledge, beliefs, attit...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016